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    Frontiers in Pharmacology of Neurotransmitters

    Numerous phenomenal advances have been made towards understanding the role of neurotransmitters in the pathophysiology of neurological disorders, and these have resulted in a large number of novel molecules with the potential to revolutionize the treatment and prevention of such disorders. This book provides a comprehensive and detailed explanation of brain neurotransmitters and their receptors and associated channels.It includes a basic introduction, and also discusses the functions and recent advances and their pharmacology, highlighting the role of various computer aided drug design (CADD) strategies for the development of therapeutic ligands to modulate these receptors/ion channels.Written in an easy-to-read style, it is intended for neuroscience and pharmaceutical students and researchers working in the area of brain neurotransmitters.

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  • Innovation Competency Model : Shaping Faculty Academic Innovation Development in China's Higher Education
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    This book explores how education can be used as a tool to promote sustainability practices as the world faces huge challenges related to climate change and public health.The chapters consider all types of literacy approaches that fall under the umbrella of Education for Sustainable Development (ESD).These approaches include scientific literacy, ecological literacy, health literacy, education on climate change and climate resilience, environmental education and others linking education, global health, and the environment more broadly. “Education” is used in the widest sense to incorporate non-formal, informal and formal/school settings.This volume will help to bring these interconnected areas together and interrogate their research methods, assumptions, field-based application and their policy potential.Taking a critical approach to ESD, the book suggests new pedagogies, tools, and technologies to strengthen the way we educate about sustainability issues and go beyond the current thinking about ESD.The book includes a foreword by Jeffrey Sachs, Director of the Center for Sustainable Development at Columbia University, USA.

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  • Digital Holocaust Memory, Education and Research
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    This book explores the diverse range of practical and theoretical challenges and possibilities that digital technologies and platforms pose for Holocaust memory, education and research.From social media to virtual reality, 360-degree imaging to machine learning, there can be no doubt that digital media penetrate practice in these fields.As the Holocaust moves beyond living memory towards solely mediated memory, it is imperative that we pay critical attention to the way digital technologies are shaping public memory and education and research.Bringing together the voices of heritage and educational professionals, and academics from the arts and humanities and the social sciences, this interdisciplinary collection explores the practicalities of creating digital Holocaust projects, the educational value of such initiatives, and considers the extent to which digital technologies change the way we remember, learn about and research the Holocaust, thinking through issues such as ethics, embodiment, agency, community, and immersion.At its core, this volume interrogates the extent to which digital interventions in these fields mark an epochal shift in Holocaust memory, education and research, or whether they continue to be shaped by long-standing debates and guidelines developed in the broadcast era.

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  • Where exactly are neurotransmitters formed?

    Neurotransmitters are formed in the axon terminals of neurons. These are the small, bulb-like structures at the end of the neuron's axon. Within the axon terminals, neurotransmitters are synthesized from various precursors and then stored in vesicles until they are released into the synapse to transmit signals to other neurons. The process of neurotransmitter formation and release is crucial for communication between neurons and for the proper functioning of the nervous system.

  • Can pleasure be specifically removed through neurotransmitters?

    Yes, pleasure can be specifically removed through neurotransmitters. For example, drugs that target the dopamine system, such as certain antipsychotic medications, can reduce feelings of pleasure and reward. By altering the levels of neurotransmitters in the brain, it is possible to dampen or eliminate the experience of pleasure in certain situations. However, it is important to note that this can have negative consequences on overall mental health and well-being.

  • What happens if neurotransmitters are not removed?

    If neurotransmitters are not removed from the synaptic cleft, they can continue to stimulate the postsynaptic neuron, leading to prolonged signaling and potential overstimulation. This can disrupt the normal functioning of the nervous system and lead to issues such as anxiety, depression, or other neurological disorders. Additionally, the accumulation of neurotransmitters in the synaptic cleft can also interfere with the release of new neurotransmitters, further disrupting communication between neurons. Therefore, the timely removal of neurotransmitters is crucial for maintaining proper neuronal function.

  • What are the neurotransmitters in the brain?

    Neurotransmitters are chemical messengers that transmit signals between neurons in the brain. Some of the major neurotransmitters in the brain include serotonin, dopamine, norepinephrine, and gamma-aminobutyric acid (GABA). These neurotransmitters play important roles in regulating mood, emotions, cognition, and various physiological functions. Imbalances in these neurotransmitters have been linked to various mental health disorders such as depression, anxiety, and schizophrenia.

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    Even though the number of working women has steadily increased over the last few years, women are still significantly under-represented in STEM activities (i.e. mathematics, informatics, science and technology). In order to eliminate this under-representation, numerous education policies and corporate initiatives, particularly in the recent past, have been aimed at increasing women's enthusiasm for STEM activities and professions.According to the latest surveys, however, it is clear that these efforts have not yet led to the desired success.Compared to their male counterparts, women continue to do fewer STEM activities. One possible reason for this is that relatively little is yet known about the concrete impact of the above education policies on working with innovation and technology: What are the gender differences between women and men?Is it enough to recognize these differences, or should these differences ideally not only be recognized, but also treated appropriately or even encouraged? This anthology deals with current topics in technology and innovation management against the background of these and other gender-relevant aspects.Empirical analyses and experiments in collaboration with companies from various sectors provide a sound scientific basis on which new results and findings are presented: How do women and men deal with creativity and competition?How are technologies applied and how can differences in access to technology be deduced? Answers to these and other questions help decision-makers in politics and business to proactively use the differences between women and men to motivate women to work in the STEM field and to strengthen them by acknowledging existing differences.

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  • Digital Education : Security, Readiness, and Technology Enhancement
    Digital Education : Security, Readiness, and Technology Enhancement

    With the onset of the COVID-19 pandemic, the education world has had to adjust to remote learning.This new book provides important research on digital pedagogies and assessment to demonstrate how technology can be effectively employed for an effective global digital learning environment. This new title brings together professional scientists and senior researchers to discuss the challenges today’s teachers and teacher-educators face in their practice.It also provides vital guidance to universities on how to develop faculty capacity to teach online.It addresses on-line learning and on-line teaching modes using the latest research, helping faculty members to design an effective digital teaching modes using evidence-based practices. Based on the expanding prospect to respond to the rise of online enrollments and the decline of face-to face education, this new book provides an important overview of digital technology-enhanced education for the 21st century STEM teachers.It examines the modern aspects of online learning by adjusting teaching practices to reflect the growing role of digital technologies.The book also features student interaction and discussion of its core themes by providing a comprehensive understanding of the technological capabilities available to them and includes research-informed and evidence-based technology integration models and instructional strategies. Readers of this reference book will learn how to adjust their practices to reflect the increasing role of digital technologies and will be encouraged to consider how digital education can prepare us all for a modern and completely new ‘information society.’ This new book is written for distance education courses for better managing online educational systems and provides readers with advanced information needed for e-learning programs in a manner that they will be capable of distinguishing among proper applications of distance education.This book is intended to support fair access to engaging digital-age education opportunities for instructional designers, faculty developers and STEM learners who take an active interest in improving online teaching.

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  • Research Methods for Education in the Digital Age
    Research Methods for Education in the Digital Age

    What is research in education? And what is it for in a digital age? Reflecting upon these questions, this engaging introduction provides critical discussion about the dilemmas of researching education in the digital age and ways forward for research in this complex area. Research Methods for Education in the Digital Age begins by outlining forms of education that are seen as digital, such as virtual, blended, immersive learning and examining the extent to which these are different or just adapted versions of earlier methods and approaches to education.Maggi Savin-Baden and Gemma Tombs explore current practices in research, identifying the successful adoption and adaption of theories and present practical guidance on new and emerging methodologies, methods, and analytical practices for undertaking educational research.New methodologies discussed include digital arts-based inquiry and digital visual methodologies, as well as adaptations of widely used methodologies such as ethnography, for the specific needs of researching digital teaching and learning. The book outlines the major challenges faced by today's digital researchers, exploring approaches to digital ethics, the relationship between qualitative and quantitative data in the digital age, digital data representations and portrayal and suggests helpful ways of dealing with the complexities and ethical challenges of undertaking research in and for digital spaces.Using case studies, research tips, a glossary and annotated further reading, the authors take a step by step approach from conceptualizing the research ideas, selecting the appropriate method to the dissemination of the findings. At a time when education is changing rapidly with digital and technological advances, Research Methods for Education in the Digital Age is essential reading for researchers wanting to undertake sound and rigorous research in the digital domain.

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  • Can one specifically remove pleasure through neurotransmitters?

    It is possible to influence pleasure through neurotransmitters by affecting the release, reuptake, or reception of certain neurotransmitters in the brain. For example, drugs such as opioids can increase feelings of pleasure by binding to opioid receptors and increasing the release of dopamine. Conversely, certain medications or conditions can decrease pleasure by reducing the activity of dopamine or other neurotransmitters. However, it is not possible to specifically and completely remove pleasure through neurotransmitters without also affecting other essential brain functions. The brain is a complex system, and pleasure is influenced by a combination of neurotransmitters and neural circuits.

  • Is the enzyme inhibited for the destruction of neurotransmitters?

    Yes, enzymes can be inhibited for the destruction of neurotransmitters. For example, the enzyme monoamine oxidase (MAO) is responsible for breaking down neurotransmitters such as serotonin, dopamine, and norepinephrine. Certain drugs, such as MAO inhibitors, can block the activity of MAO, leading to an increase in neurotransmitter levels in the brain. This can have therapeutic effects in conditions such as depression and anxiety.

  • Does it lead to a prolonged excitation when the neurotransmitters...

    Yes, prolonged excitation can occur when neurotransmitters are not properly reabsorbed or broken down. This can happen when there is a dysfunction in the reuptake process or when there is an excess of neurotransmitters in the synaptic cleft. Prolonged excitation can lead to overstimulation of the postsynaptic neuron, which can have negative effects on the nervous system and contribute to conditions such as anxiety, seizures, or neurodegenerative diseases. Therefore, proper regulation of neurotransmitter levels and reuptake processes is crucial for maintaining healthy nervous system function.

  • How does the release of neurotransmitters occur directly before death?

    As the body approaches death, the brain experiences a surge of electrical activity, leading to the release of neurotransmitters. This surge in activity is thought to be the brain's response to the lack of oxygen and other metabolic changes that occur as the body shuts down. The release of neurotransmitters, such as dopamine and glutamate, can contribute to the hallucinations and altered states of consciousness that some people report experiencing as they near death. This surge in neurotransmitter release may also play a role in the phenomenon of near-death experiences.

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