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  • Histamine Receptors as Drug Targets
    Histamine Receptors as Drug Targets

    This book illustrates the current state-of-the-art in histamine research, with a focus on the appropriate methodologies to investigate the pharmacological properties and the therapeutic exploitation of HRs and their ligands.In addition, the range of techniques described provides an introduction to complementary cross-methodological disciplines beyond these fields.This multi-disciplinary approach is required to define the ‘decision gates’ that determine the development of more effective and safer therapeutic options for many forms of highly prevalent and debilitating diseases, such as asthma, dementias, dermatitis, and arthritis.Written for the Methods in Pharmacology and Toxicology series, chapters concentrate on practical, hands-on protocols from experts in the techniques. Authoritative and thorough, Histamine Receptors as Drug Targets seeks to aid pharmacologists, biochemists, drug discovery researchers, molecular biologists, chemists, toxicologists, lab scientists, medical doctors, principle investigators, research scientists, lab directors and technicians, as well as graduate students around the world in pursuing the study of this vital scientific area.

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  • Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems
    Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems

    Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems will cover the up-to-date biosensor technologies used for the detection of bacteria.Written by the world's most renowned and learned scientists each in their own area of expertise, Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems is the first title to cover this expanding research field.

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  • Chronic Lymphocytic Leukemia : Pathobiology,  B Cell Receptors, Novel Mutations, Clonal Evolution
    Chronic Lymphocytic Leukemia : Pathobiology, B Cell Receptors, Novel Mutations, Clonal Evolution

    This text provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for pathologists and clinical hematologists/oncologists with an interest in chronic lymphocytic leukemia.This book is designed to provide a concise yet comprehensive summary of the traditional and new definitions, prognostic markers, the pathobiology and newer hierarchal classification based on molecular genetics/chromosomal abnormalities. It will include the most up-to-date scientific and clinical information and bring together subject matter that is usually covered separately in various specialties of hematopathology, molecular pathology, basic science and immunology.The book is written in an easy to comprehend format with emphasis on the science and illustrations to explain the same.It is therefore intended to intrigue, the junior resident and the senior pathologists/clinical oncologists and anyone who would like to keep up with this rapidly growing field.

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  • Innovation Competency Model : Shaping Faculty Academic Innovation Development in China's Higher Education
    Innovation Competency Model : Shaping Faculty Academic Innovation Development in China's Higher Education

    Contributing to the discussion over China's higher education development, this book takes a theoretical approach to address the topic of university academics' innovation by introducing an academic innovation competency model, exploring the contexts, concepts and practices.The innovation competency model comprises three interdependent dimensions, including the academic internal drive vitality, the academic synthesizing refined ability and the academic suspected and introspective ability.By enriching the theory of professional development of university teachers, these three dimensions will help advance the reform of college personnel systems and ultimately improve the quality of China's higher education. The book will be valuable to researchers, students and stakeholders hoping to learn about education reform in China, or to those who study higher education management and comparative education.

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  • When are receptors formed?

    Receptors are formed during early development in the womb. They are essential proteins that are embedded in cell membranes and play a crucial role in transmitting signals from the external environment to the inside of the cell. The formation of receptors is a complex process that involves specific genetic instructions and protein synthesis. Once formed, receptors continue to be expressed and regulated throughout an individual's life to ensure proper cellular communication and function.

  • Are receptors sensory cells?

    Receptors are not sensory cells themselves, but they are specialized proteins located on the surface of sensory cells. These receptors are responsible for detecting and responding to specific stimuli, such as light, sound, taste, or smell. When a receptor is activated by a stimulus, it triggers a series of biochemical reactions within the sensory cell, ultimately leading to the generation of a sensory signal that can be transmitted to the brain for processing. Therefore, while receptors are not sensory cells, they play a crucial role in the sensory process by detecting and transducing stimuli into neural signals.

  • What are hormone receptors?

    Hormone receptors are proteins located on the surface or within the cells of target tissues that are capable of binding to specific hormones. When a hormone binds to its receptor, it triggers a series of cellular responses that ultimately lead to changes in gene expression, cell function, or metabolism. Hormone receptors are crucial for the regulation of various physiological processes in the body, including growth, metabolism, and reproduction. Different types of hormones, such as steroid hormones, thyroid hormones, and peptide hormones, have specific receptors that they bind to in order to exert their effects on target cells.

  • Do organs have pain receptors?

    No, organs themselves do not have pain receptors. Pain receptors, also known as nociceptors, are specialized nerve cells that detect tissue damage and send signals to the brain to indicate pain. While organs do not have pain receptors, the tissues surrounding organs, such as the lining of the abdomen or chest, can contain nociceptors and can transmit pain signals if they are damaged or inflamed.

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  • Rethinking Education for Sustainable Development : Research, Policy and Practice
    Rethinking Education for Sustainable Development : Research, Policy and Practice

    This book explores how education can be used as a tool to promote sustainability practices as the world faces huge challenges related to climate change and public health.The chapters consider all types of literacy approaches that fall under the umbrella of Education for Sustainable Development (ESD).These approaches include scientific literacy, ecological literacy, health literacy, education on climate change and climate resilience, environmental education and others linking education, global health, and the environment more broadly. “Education” is used in the widest sense to incorporate non-formal, informal and formal/school settings.This volume will help to bring these interconnected areas together and interrogate their research methods, assumptions, field-based application and their policy potential.Taking a critical approach to ESD, the book suggests new pedagogies, tools, and technologies to strengthen the way we educate about sustainability issues and go beyond the current thinking about ESD.The book includes a foreword by Jeffrey Sachs, Director of the Center for Sustainable Development at Columbia University, USA.

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  • Digital Holocaust Memory, Education and Research
    Digital Holocaust Memory, Education and Research

    This book explores the diverse range of practical and theoretical challenges and possibilities that digital technologies and platforms pose for Holocaust memory, education and research.From social media to virtual reality, 360-degree imaging to machine learning, there can be no doubt that digital media penetrate practice in these fields.As the Holocaust moves beyond living memory towards solely mediated memory, it is imperative that we pay critical attention to the way digital technologies are shaping public memory and education and research.Bringing together the voices of heritage and educational professionals, and academics from the arts and humanities and the social sciences, this interdisciplinary collection explores the practicalities of creating digital Holocaust projects, the educational value of such initiatives, and considers the extent to which digital technologies change the way we remember, learn about and research the Holocaust, thinking through issues such as ethics, embodiment, agency, community, and immersion.At its core, this volume interrogates the extent to which digital interventions in these fields mark an epochal shift in Holocaust memory, education and research, or whether they continue to be shaped by long-standing debates and guidelines developed in the broadcast era.

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  • Gender Differences in Technology and Innovation Management : Insights from Experimental Research
    Gender Differences in Technology and Innovation Management : Insights from Experimental Research

    Even though the number of working women has steadily increased over the last few years, women are still significantly under-represented in STEM activities (i.e. mathematics, informatics, science and technology). In order to eliminate this under-representation, numerous education policies and corporate initiatives, particularly in the recent past, have been aimed at increasing women's enthusiasm for STEM activities and professions.According to the latest surveys, however, it is clear that these efforts have not yet led to the desired success.Compared to their male counterparts, women continue to do fewer STEM activities. One possible reason for this is that relatively little is yet known about the concrete impact of the above education policies on working with innovation and technology: What are the gender differences between women and men?Is it enough to recognize these differences, or should these differences ideally not only be recognized, but also treated appropriately or even encouraged? This anthology deals with current topics in technology and innovation management against the background of these and other gender-relevant aspects.Empirical analyses and experiments in collaboration with companies from various sectors provide a sound scientific basis on which new results and findings are presented: How do women and men deal with creativity and competition?How are technologies applied and how can differences in access to technology be deduced? Answers to these and other questions help decision-makers in politics and business to proactively use the differences between women and men to motivate women to work in the STEM field and to strengthen them by acknowledging existing differences.

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    Science, Technology And Innovation Indicators : Lessons from the Development Experience in Africa


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  • Why are there 1 million receptors per cm2 if there are 100,000 receptors per cm2?

    There may be 1 million receptors per cm2 if there are 100,000 receptors per cm2 because the receptors may be densely packed together, allowing for more receptors to fit within the same area. Additionally, having a higher density of receptors may increase the sensitivity and efficiency of the sensory system in detecting and responding to stimuli. This high density of receptors may be particularly important in areas of the body that require a high level of sensitivity, such as the fingertips or the tongue.

  • Which medications block the nicotine receptors?

    Medications such as varenicline (Chantix) and bupropion (Zyban) are known to block nicotine receptors in the brain. By blocking these receptors, these medications reduce the pleasurable effects of nicotine, making it easier for individuals to quit smoking. These medications are often used as part of a comprehensive smoking cessation program to help individuals overcome their addiction to nicotine.

  • Where are pain receptors located in the body?

    Pain receptors, also known as nociceptors, are located throughout the body. They are found in the skin, muscles, joints, organs, and even in the walls of blood vessels. These receptors are specialized nerve endings that detect potentially harmful stimuli, such as temperature, pressure, or chemicals, and send signals to the brain to alert the body of potential damage.

  • Do Zolpidem and/or Benzodiazepines affect dopamine receptors?

    Zolpidem and benzodiazepines primarily act on the GABA-A receptors in the brain, which are involved in the regulation of anxiety and sleep. While they do not directly affect dopamine receptors, they can indirectly influence dopamine levels in the brain by modulating the activity of other neurotransmitter systems. For example, benzodiazepines have been shown to indirectly affect dopamine release in certain brain regions. However, their primary mechanism of action is not through direct interaction with dopamine receptors.

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