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  • Signaling by Receptor Tyrosine Kinases
    Signaling by Receptor Tyrosine Kinases


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    Receptor Schellenberg 20018 Wireless Blind

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  • Maxxis Receptor Gravel Tyre - 650 x 47
    Maxxis Receptor Gravel Tyre - 650 x 47

    The Maxxis Receptor Gravel Tyre combines smooth rolling performance with reliable traction. Its semi-slick design makes it perfect for hard-packed dirt and light gravel surfaces. A low-profile centre tread provides fast rolling on any surface, while shoulder knobs ensure excellent grip in corners. This tyre excels at maintaining speed without sacrificing stability.Key Features and Benefits:120 TPI tubeless ready casing: The high-thread count offers increased flexibility and ride comfort. This results in a smoother ride on mixed terrain.Dual compound: The use of two rubber compounds improves traction and durability. You get better grip in wet conditions and longer tyre life.Semi-slick centre tread: The low-profile centre provides excellent rolling resistance, allowing for faster speeds on hard surfaces. You can maintain high efficiency on smooth and rough terrain.Shoulder knobs for cornering traction: These small knobs ensure you remain stable and controlled when turning on loose or uneven surfaces. This gives you confidence and safety in varied conditions.Maxxis Technologies (Compounds & Casings):EXO - EXO is a cut and abrasion-resistant material added to the sidewalls of many Maxxis mountain bike and gravel tyres. This densely woven fabric is lightweight and highly flexible, ensuring that the performance of the tyre remains unaffected. Choose EXO Protection for enhanced durability for gravel, XC, and light-duty trail riding.The Maxxis Receptor Gravel Tyre is designed for riders who value speed and control. It balances the need for fast-rolling efficiency with grip and durability. This makes it ideal for those who cycle on mixed terrains, from pavement to light gravel, without compromising performance. Its durable build ensures long-lasting use, even in challenging conditions.Get the Maxxis Receptor today to experience the perfect blend of speed, grip, and durability for your next ride.

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  • What is a receptor molecule?

    A receptor molecule is a protein located on the surface of a cell that binds to specific signaling molecules, such as hormones or neurotransmitters. When the signaling molecule binds to the receptor, it triggers a cellular response, such as a change in gene expression or activation of a signaling pathway. Receptor molecules are crucial for communication between cells and for coordinating various physiological processes within the body.

  • Can you explain the receptor potential?

    The receptor potential is a change in membrane potential that occurs in sensory receptor cells in response to a stimulus. When a stimulus such as light, sound, or touch activates a sensory receptor, it causes ion channels in the cell membrane to open or close, leading to a change in membrane potential. This change in membrane potential triggers the generation of action potentials, which are then transmitted to the central nervous system for processing and interpretation. The receptor potential serves as the initial step in converting a sensory stimulus into an electrical signal that can be transmitted to the brain for perception.

  • Are regulator and activator proteins also hormone receptor complexes?

    Regulator and activator proteins are not the same as hormone receptor complexes, although they may interact with hormone receptor complexes to modulate their activity. Hormone receptor complexes are specific proteins that bind to hormones and initiate a cellular response, while regulator and activator proteins are involved in regulating the activity of these hormone receptor complexes. Regulator and activator proteins can enhance or inhibit the activity of hormone receptor complexes, but they are not themselves hormone receptor complexes.

  • Why does the receptor potential decrease towards the axon hillock?

    The receptor potential decreases towards the axon hillock because the axon hillock acts as a site of integration for incoming signals from various receptors. As the receptor potential travels towards the axon hillock, it undergoes summation with other incoming signals. This integration process helps determine whether an action potential will be generated and propagated down the axon. The decrease in receptor potential towards the axon hillock is crucial for the neuron to make decisions about whether to transmit the signal further.

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  • Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders
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    Overexpression of receptor tyrosine kinases (RTKs) has been implicated in cancer.Increasing evidence suggests that dysregulation of RTKs is reported in many neurodegenerative and psychiatric disorders. Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders provides a fundamental, pragmatic map of RTKs structure, activation, functions, mechanism of action, gene regulation, and signaling pathways in developing central nervous system (CNS), adult normal CNS, neurodegenerative and psychiatric disorders.Additionally, the structure, function, activation, and therapeutic potential of many growth factors have been covered.Here, international experts in the field offer a comprehensive discussion of results of pre-clinical and clinical studies of repositioning of anti-cancer receptor tyrosine kinase inhibitors (RTKIs) and other promising protein kinase inhibitors in various neurodegenerative disorders including, Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, Huntington's disease, and multiple sclerosis, and psychiatric disorders including, anxiety, depression, alcohol use disorder, and schizophrenia.In addition, the book discusses the obstacles and opportunities for the potential repositioning of kinase inhibitors in neurodegenerative and psychiatric disorders.

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    POC Unisex Receptor BUG in Uranium Black - Black / Small

    Unisex Poc Receptor BUG in Uranium Black has won awards for both design and safety. The patented system with double overlapping shells protects from sharp objects, while still providing excellent ventilation.     Ventilated double shell system EPS liner Detachable ear pads and neck roll Compatible with the Communication Neck roll with powerful Beats by Dre speakers and microphone Attachable goggle clip Available in sizes XS-XXL Also available in white

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  • What is the difference between an acceptor and a receptor molecule?

    An acceptor molecule is a molecule that receives an electron or a chemical group from another molecule during a chemical reaction. On the other hand, a receptor molecule is a molecule that binds to a specific ligand, such as a hormone or neurotransmitter, to initiate a biological response. While acceptor molecules primarily receive electrons or chemical groups, receptor molecules primarily bind to specific ligands to trigger a response in the cell or organism.

  • What is the effect of barbiturates on the GABA-A receptor?

    Barbiturates enhance the inhibitory effects of the neurotransmitter GABA on the GABA-A receptor. They bind to a specific site on the receptor and increase the duration of the chloride channel opening, leading to hyperpolarization of the neuron and inhibition of neuronal activity. This results in sedative, hypnotic, and anxiolytic effects, making barbiturates commonly used as central nervous system depressants. Prolonged use of barbiturates can lead to tolerance, dependence, and potentially dangerous withdrawal symptoms.

  • How is a receptor potential generated based on the ion theory?

    A receptor potential is generated based on the ion theory through the activation of ion channels in response to a stimulus. When a stimulus is detected by a sensory receptor, it causes ion channels in the receptor membrane to open or close, allowing specific ions to flow into or out of the cell. This movement of ions creates a change in the membrane potential, known as the receptor potential. The magnitude of the receptor potential is directly related to the strength of the stimulus, with stronger stimuli leading to larger changes in membrane potential.

  • What happens when the receptor potential reaches the central nervous system?

    When the receptor potential reaches the central nervous system, it triggers the generation of action potentials in sensory neurons. These action potentials travel along the sensory neurons to the brain, where they are processed and interpreted. The brain then generates a response or perception based on the information received from the receptor potential. This process allows us to sense and respond to various stimuli in our environment.

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