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  • Mitochondrial Diseases : Volume 194
    Mitochondrial Diseases : Volume 194

    Mitochondrial Diseases, Volume 194 presents the most common clinical manifestations, providing an up-to-date summaries on the clinical presentations, diagnostic processes, genetic counseling and treatment options in mitochondrial diseases.Contents include specialist biochemical analyses and targeted molecular genetic testing, as well as first-line genome-wide sequencing to accelerate speed of diagnosis while avoiding time-consuming, expensive and invasive investigations.Establishing a genetic diagnosis allows patients with mitochondrial diseases to have reproductive options, all of which are covered within. This book is intended for neurologists to help them recognize and manage patients with mitochondrial diseases.

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  • Mitochondrial Regulation : Methods and Protocols
    Mitochondrial Regulation : Methods and Protocols

    In this volume expert researchers in the field detail the many methods for further research into regulation of mitochondrial function.Chapters focus on mitochondria with other cellular components, discussing how these interactions influence the dynamics of mitochondrial structure and biogenesis.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Mitochondrial Regulation: Methods and Protocols seeks to aid advanced undergraduates, graduates, postgraduates, and beginning researchers in the areas of molecular and cellular biology, biochemistry and bioenergetics.

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  • Mitochondrial DNA, Mitochondria, Disease and Stem Cells
    Mitochondrial DNA, Mitochondria, Disease and Stem Cells

    This volume investigates how the mitochondrial genome is transmitted, segregated, and inherited.It starts by describing mtDNA mutations and deletions and how these impact on the offspring’s well-being.It progresses to discuss how mutations to the mtDNA-nuclear-encoded transcription, replication and translational factors lead to mtDNA-depletion syndromes and how these affect cellular function and lead to the pathology of human mitochondrial disease.It also highlights the importance of the mitochondrial assembly factors and how mutations to these can lead to mitochondrial disease.The reader is then introduced to how mtDNA is transmitted through the oocyte and how stem cells can be used to study mitochondrial biogenesis and mtDNA replication and transcription in undifferentiated pluripotent and differentiating cells and how mitochondria adapt during this process.It then discusses how diseases like cancer are initiated and regulated by mutations to mitochondrial DNA and dysfunctional mitochondria.Finally, it draws on assisted reproductive technologies to discuss how some of these approaches might be adapted to prevent the transmission of mutant and deleted mtDNA from one generation to the next.

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  • Mitochondrial Medicine : Volume 3: Manipulating Mitochondria and Disease- Specific Approaches
    Mitochondrial Medicine : Volume 3: Manipulating Mitochondria and Disease- Specific Approaches

    This second edition offers 88 chapters divided among three volumes providing the most comprehensive source of know-how in the wide-ranging field of Mitochondrial Medicine.Volume III guides readers through chapters on intercellular mitochondrial transfer, Cytoplasmic transfer methods, Ndufs4 knockout mouse, in vivo assessment of mitochondrial oxygen consumption, mitochondrial network analysis by imaging, mitochondrial respiration in platelets, Heterologous Inferential Analysis (HIA), bioenergetic profiling, integrative methods for studying cardiac energetics, and isolation and deep sequencing of mitochondrial DNA.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, application details for both the expert and non-expert reader, and tips on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Mitochondrial Medicine, Second Edition, Volume 3: Manipulating Mitochondria and Disease- Specific Approaches aims to be a comprehensive source of know-how in the wide-ranging field of Mitochondrial Medicine.

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  • What is mitochondrial inheritance?

    Mitochondrial inheritance refers to the passing down of genetic material contained within the mitochondria from one generation to the next. Unlike nuclear DNA, which is inherited from both parents, mitochondrial DNA is inherited exclusively from the mother. This is because the mitochondria in the sperm are usually destroyed after fertilization, so only the mother's mitochondria are passed on to the offspring. Mitochondrial inheritance can lead to a variety of inherited mitochondrial disorders, as mutations in mitochondrial DNA can affect the function of the mitochondria and lead to various health issues.

  • What is a mitochondrial genome?

    A mitochondrial genome is the genetic material found within the mitochondria, which are small structures within cells that are responsible for producing energy. Unlike the nuclear genome, which is inherited from both parents, the mitochondrial genome is inherited exclusively from the mother. It is a circular piece of DNA that contains genes necessary for the mitochondria to function, including those involved in energy production and metabolism. Mutations in the mitochondrial genome can lead to a variety of genetic disorders and diseases.

  • Why do evolutionary researchers use mitochondrial DNA (mtDNA) to analyze human ancestry?

    Evolutionary researchers use mitochondrial DNA (mtDNA) to analyze human ancestry because it is inherited exclusively from the mother, making it a useful tool for tracing maternal lineages. Since mtDNA is passed down without recombination, it accumulates mutations at a relatively constant rate, allowing researchers to estimate the time of divergence between different populations. Additionally, mtDNA is present in high copy numbers in cells, making it easier to extract and analyze from ancient or degraded samples. Overall, mtDNA provides valuable information about the evolutionary history and migration patterns of human populations.

  • What is the significance of Adam of the Y chromosome and Mitochondrial Eve?

    Adam of the Y chromosome and Mitochondrial Eve are hypothetical individuals who represent the most recent common ancestors of all living humans in their respective genetic lineages. They are significant because they provide insights into human evolution and the origins of our species. By tracing back genetic markers found on the Y chromosome and mitochondrial DNA, scientists can estimate when and where these individuals lived, shedding light on the migration patterns and genetic diversity of early human populations.

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  • Innovation Competency Model : Shaping Faculty Academic Innovation Development in China's Higher Education
    Innovation Competency Model : Shaping Faculty Academic Innovation Development in China's Higher Education

    Contributing to the discussion over China's higher education development, this book takes a theoretical approach to address the topic of university academics' innovation by introducing an academic innovation competency model, exploring the contexts, concepts and practices.The innovation competency model comprises three interdependent dimensions, including the academic internal drive vitality, the academic synthesizing refined ability and the academic suspected and introspective ability.By enriching the theory of professional development of university teachers, these three dimensions will help advance the reform of college personnel systems and ultimately improve the quality of China's higher education. The book will be valuable to researchers, students and stakeholders hoping to learn about education reform in China, or to those who study higher education management and comparative education.

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  • Life Extension Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support, 100mg - 30 softgels
    Life Extension Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support, 100mg - 30 softgels

    Description Ingredients   Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support combines our highly bioavailable ubiquinol form of coenzyme Q10 with PrimaVie shilajit, an adaptogen shown to increase absorption and promote cardiovascular health. This patented formula is designed to support youthful cellular energy production and benefit high-energy organs like the brain, liver, and kidneys. With regular use, it can help offset the natural decline of CoQ10 as we age, providing powerful cardiovascular support and antioxidant benefits.   Life Extension Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support, 100mg - 30 softgels Food supplement in softgels. Containing various oils Nutrition Facts Serving Size: 1 Softgel Servings Per Container: 30 Amount Per Serving %RI* Calories 5 kcal Total Fat 0.5 g 1% Ubiquinol (as Kaneka Ubiquinol) 100 mg PrimaVie Shilajit fulvic acid complex 100 mg *Percent Daily Values are based on a 2,000 calorie diet. Your daily values may be higher or lower depending on your calorie needs. INGREDIENTS: Ubiquinol (as Kaneka Ubiquinol), PrimaVie Shilajit fulvic acid complex OTHER INGREDIENTS: Sunflower oil, gelatin, glycerin, purified water, beeswax, sunflower lecithin, annatto color. RECOMMENDED USE: Take one (1) softgel daily with food, or as recommended by a healthcare practitioner. WARNINGS: Keep out of reach of children. Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged. When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition of if you are pregnant or lactating. Unit type: Softgels Net weight: 40 Product Barcode: 737870143734

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  • Life Extension Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support 100 mg 60 Softgels
    Life Extension Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support 100 mg 60 Softgels

    Our patented ubiquinol is highly bioavailable, which means it's easy for the body to absorb. Combined with PrimaVie shilajit the rate of absorption increases to help promote the body's youthful cellular energy production. Read More Description Ingredients How to Use CoQ10 is a vital nutrient that supports heart health and cellular energy by protecting important organs and DNA. As we age, levels of CoQ10 naturally decline, making supplementation necessary. Life Extension's Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support offers patented, highly-absorbable ubiquinol and PrimaVie shilajit for even greater cellular energy output. Sunflower oil, gelatin, glycerin, purified water, beeswax, sunflower lecithin, annatto colour. Take one (1) softgel daily with food, or as recommended by a healthcare professional.

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  • Life Extension Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support 50 mg 100 Softgels
    Life Extension Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support 50 mg 100 Softgels

    Our patented ubiquinol is highly bioavailable, which means it's easy for the body to absorb. Combined with PrimaVie shilajit the rate of absorption increases to help promote the body's youthful cellular energy production. Read More Description Ingredients How to Use CoQ10, an essential nutrient for mitochondrial function and cellular energy, is concentrated in high-energy organs such as the brain, liver, kidneys, and heart. Life Extension offers a highly bioavailable form of ubiquinol CoQ10 in a patented delivery system that absorbs up to 8 times better than traditional ubiquinone. Combined with shilajit, this formula provides even greater cellular energy support and promotes a healthy heart. Get your supply today! Sunflower oil, gelatin, glycerin, purified water, beeswax, sunflower lecithin, annatto colour. Take one (1) softgel once or twice daily with food, or as recommended by a healthcare professional.

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  • Does market research hinder innovation in business administration?

    Market research does not necessarily hinder innovation in business administration. In fact, it can provide valuable insights into consumer needs and preferences, helping businesses to develop innovative products and services that meet market demands. By understanding market trends and customer behavior, businesses can identify opportunities for innovation and stay ahead of competitors. However, relying too heavily on market research without allowing room for creativity and risk-taking can limit the potential for groundbreaking innovations. It is important for businesses to strike a balance between leveraging market research and fostering a culture of innovation to drive success in business administration.

  • What is Digital Technology 2?

    Digital Technology 2 is a course that builds upon the foundational concepts introduced in Digital Technology 1. It delves deeper into topics such as programming, web development, data analysis, and cybersecurity. Students will further develop their skills in using digital tools and technologies to solve real-world problems and gain a more advanced understanding of how technology impacts society. The course aims to prepare students for a career in the rapidly evolving field of digital technology.

  • Who knows the company Digital Innovation Ventures GmbH in Zug, Switzerland?

    Digital Innovation Ventures GmbH in Zug, Switzerland is likely known by individuals in the tech industry, potential investors, business partners, and employees or former employees of the company. Additionally, local residents of Zug who are familiar with the business landscape in the area may also know of the company.

  • Will the development of technology ever stop?

    It is unlikely that the development of technology will ever stop. As long as there are new problems to solve and new opportunities to explore, there will be a need for technological innovation. Additionally, the pace of technological advancement has been accelerating in recent years, with new breakthroughs and discoveries constantly pushing the boundaries of what is possible. While the specific direction and focus of technological development may change over time, it is likely that the overall trend of progress will continue.

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