Products related to Chromatin:
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Chromatin : Structure, Function, and History
Chromatin: Structure, Function, and History brings the reader up to date on the remarkable progress made in chromatin research over the course of the past 50 years.Coverage includes the basics of chromatin biology, beginning with the discoveries that culminated in the recognition of the nucleosome as the basic subunit of chromatin.Chromatin folding, nucleosome positioning, and histone variants are discussed, as well as research on chromatin modifications and remodeling, which exploded in the early to mid-1990s and led to widespread interest in epigenetics.Considerable attention is given to methods and experiments that led to key insights, and recent developments such as the use of genome-wide approaches and innovations in imaging approaches are also emphasized.By providing historical background together with detailed discussion of contemporary studies, the book aims to instill in the reader an appreciation not only of our current knowledge of chromatin structure and function, but also of the remarkable path that has taken chromatin to the forefront of modern research.
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Chromatin Readers in Health and Disease : Volume 35
Chromatin Readers in Health and Disease, Volume 35, a new release in the Translational Epigenetics series, gathers and makes actionable our current understanding of how chromatin readers regulate access to genetic information, and how their aberrant regulation can contribute to human pathologies.Chromatin readers discussed include 14-3-3 Dinshaw, ADD, Ankyrin, BAH, BET, BIR, BRCT, bromodomains and Kac readers, chromodomains and chromobarrel readers, citrullination readers, macrodomains and poly-ADP-ribose readers, MBT, PHD and double PHD, PWWP, SUMO (H4K12) readers, Tudor and TTD, UDR and ubiquitin, WD40, YEATS (crotonyl reader), MBD, SRA, and Methyl-RNA readers. In the book, more than a dozen leaders in the field examine a range of protein readers, their relationship to human disease, and the early therapeutics that act as chromatin signaling factors to treat cancers and Huntington's disease, among other disorders.
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Innovation Competency Model : Shaping Faculty Academic Innovation Development in China's Higher Education
Contributing to the discussion over China's higher education development, this book takes a theoretical approach to address the topic of university academics' innovation by introducing an academic innovation competency model, exploring the contexts, concepts and practices.The innovation competency model comprises three interdependent dimensions, including the academic internal drive vitality, the academic synthesizing refined ability and the academic suspected and introspective ability.By enriching the theory of professional development of university teachers, these three dimensions will help advance the reform of college personnel systems and ultimately improve the quality of China's higher education. The book will be valuable to researchers, students and stakeholders hoping to learn about education reform in China, or to those who study higher education management and comparative education.
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Rethinking Education for Sustainable Development : Research, Policy and Practice
This book explores how education can be used as a tool to promote sustainability practices as the world faces huge challenges related to climate change and public health.The chapters consider all types of literacy approaches that fall under the umbrella of Education for Sustainable Development (ESD).These approaches include scientific literacy, ecological literacy, health literacy, education on climate change and climate resilience, environmental education and others linking education, global health, and the environment more broadly. “Education” is used in the widest sense to incorporate non-formal, informal and formal/school settings.This volume will help to bring these interconnected areas together and interrogate their research methods, assumptions, field-based application and their policy potential.Taking a critical approach to ESD, the book suggests new pedagogies, tools, and technologies to strengthen the way we educate about sustainability issues and go beyond the current thinking about ESD.The book includes a foreword by Jeffrey Sachs, Director of the Center for Sustainable Development at Columbia University, USA.
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What is a chromatin thread?
A chromatin thread is a structure found within the nucleus of a cell, consisting of DNA and associated proteins. It is the form that DNA takes during the interphase of the cell cycle, when the DNA is not actively being replicated or divided. The chromatin thread is essential for packaging and organizing the long strands of DNA within the nucleus, and it plays a crucial role in regulating gene expression and cell function. When the cell prepares to divide, the chromatin thread condenses further into visible chromosomes.
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Why does chromatin condense into chromosomes?
Chromatin condenses into chromosomes during cell division to ensure that the genetic material is properly distributed to the daughter cells. This condensation allows the chromosomes to be easily separated and pulled apart during the process of cell division, ensuring that each daughter cell receives a complete and accurate set of genetic information. Additionally, the condensed structure of chromosomes helps to protect the DNA from damage and tangling during the physical processes of cell division.
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Is chromatin only visible during cell division?
No, chromatin is not only visible during cell division. Chromatin is a complex of DNA and proteins that make up the genetic material in the nucleus of a cell. It is visible in both dividing and non-dividing cells. In non-dividing cells, chromatin is less condensed and appears as a diffuse network within the nucleus, while during cell division, chromatin condenses into visible chromosomes.
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What is the core-shell model of chromatin?
The core-shell model of chromatin describes the organization of chromatin within the cell nucleus. In this model, the core represents the tightly packed nucleosomes made up of DNA wrapped around histone proteins. Surrounding this core is the shell, which consists of less condensed chromatin that is more accessible for gene expression and regulation. This model helps to explain how different regions of the genome can be packaged and regulated differently within the nucleus.
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Digital Holocaust Memory, Education and Research
This book explores the diverse range of practical and theoretical challenges and possibilities that digital technologies and platforms pose for Holocaust memory, education and research.From social media to virtual reality, 360-degree imaging to machine learning, there can be no doubt that digital media penetrate practice in these fields.As the Holocaust moves beyond living memory towards solely mediated memory, it is imperative that we pay critical attention to the way digital technologies are shaping public memory and education and research.Bringing together the voices of heritage and educational professionals, and academics from the arts and humanities and the social sciences, this interdisciplinary collection explores the practicalities of creating digital Holocaust projects, the educational value of such initiatives, and considers the extent to which digital technologies change the way we remember, learn about and research the Holocaust, thinking through issues such as ethics, embodiment, agency, community, and immersion.At its core, this volume interrogates the extent to which digital interventions in these fields mark an epochal shift in Holocaust memory, education and research, or whether they continue to be shaped by long-standing debates and guidelines developed in the broadcast era.
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Gender Differences in Technology and Innovation Management : Insights from Experimental Research
Even though the number of working women has steadily increased over the last few years, women are still significantly under-represented in STEM activities (i.e. mathematics, informatics, science and technology). In order to eliminate this under-representation, numerous education policies and corporate initiatives, particularly in the recent past, have been aimed at increasing women's enthusiasm for STEM activities and professions.According to the latest surveys, however, it is clear that these efforts have not yet led to the desired success.Compared to their male counterparts, women continue to do fewer STEM activities. One possible reason for this is that relatively little is yet known about the concrete impact of the above education policies on working with innovation and technology: What are the gender differences between women and men?Is it enough to recognize these differences, or should these differences ideally not only be recognized, but also treated appropriately or even encouraged? This anthology deals with current topics in technology and innovation management against the background of these and other gender-relevant aspects.Empirical analyses and experiments in collaboration with companies from various sectors provide a sound scientific basis on which new results and findings are presented: How do women and men deal with creativity and competition?How are technologies applied and how can differences in access to technology be deduced? Answers to these and other questions help decision-makers in politics and business to proactively use the differences between women and men to motivate women to work in the STEM field and to strengthen them by acknowledging existing differences.
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Science, Technology And Innovation Indicators : Lessons from the Development Experience in Africa
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Development, Education and Learning in Sri Lanka : An International Research Journey
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What is the core-envelope model of chromatin?
The core-envelope model of chromatin describes the organization of chromatin into two distinct regions: the core, which consists of tightly packed nucleosomes made up of DNA wrapped around histone proteins, and the envelope, which surrounds the core and is composed of more loosely packed nucleosomes. This model suggests that the core region is more stable and less accessible for gene expression, while the envelope region is more dynamic and accessible for gene regulation. The core-envelope model helps to explain how chromatin structure can influence gene expression and cellular function.
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What is the difference between chromatin and chromosome?
Chromatin is the complex of DNA and proteins found in the nucleus of a cell, while a chromosome is a condensed and organized structure of chromatin that is visible during cell division. Chromatin is the uncondensed form of DNA that is actively involved in gene expression and regulation, whereas chromosomes are only visible as distinct structures when the cell is dividing. In summary, chromatin is the relaxed form of DNA, while chromosomes are the condensed and visible form of DNA.
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What is the function of a chromatin thread?
The function of a chromatin thread is to package and organize the DNA within the nucleus of a cell. It helps to compact the long strands of DNA into a more condensed structure, allowing it to fit inside the nucleus. Additionally, chromatin threads play a role in regulating gene expression by controlling which genes are accessible for transcription.
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How important are the cell nucleus and chromatin?
The cell nucleus is crucial for the overall function and survival of the cell. It contains the cell's genetic material, including DNA, which is essential for controlling the cell's activities and passing on genetic information to the next generation. Chromatin, which is the complex of DNA and proteins within the nucleus, plays a key role in regulating gene expression and packaging the genetic material. Therefore, both the cell nucleus and chromatin are vital for maintaining the integrity and function of the cell.
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